SURGERY FOR BONE TUMOURS

Primary Bone Cancer
 

The four most common types of primary bone cancer are:

• Multiple myeloma. Multiple myeloma is the most common primary bone cancer. It is a malignant tumor of bone marrow — the soft tissue in the center of many bones that produces blood cells. Any bone can be affected by this cancer.
  Multiple myeloma affects approximately seven people per 100,000 each year. According to the National Cancer Institute, more than 130,000 people are living with the disease each year. Most cases are seen in patients between the ages of 50 and 70. Multiple myeloma is typically treated with chemotherapy, radiation therapy and, occasionally, surgery.

• Osteosarcoma. Osteosarcoma is the second most common primary bone cancer. It occurs in two to five people per million each year, with most cases in teenagers and children. Most tumors develop around the knee in either the femur (thighbone) or tibia (shinbone). Other common locations include the hip and shoulder. Osteosarcoma is typically treated with chemotherapy and surgery.

• Ewing's sarcoma. Ewing's sarcoma usually occurs in patients between the ages of 5 and 20. The most common locations affected are the upper and lower leg, pelvis, upper arm, and ribs. Ewing's sarcoma is typically treated with chemotherapy and either surgery or radiation therapy.

• Chondrosarcoma. Chondrosarcoma is a malignant tumor composed of cartilage-producing cells. It is most often seen in patients between the ages of 40 and 70. Most cases occur around the hip, pelvis, or shoulder area. In most cases, surgery is the only treatment used for chondrosarcoma.
   

Benign Bone Tumors
 

There are many types of benign bone tumors, as well as some diseases and conditions that resemble bone tumors. Although these conditions are not truly bone tumors, in many cases they require the same treatment.
 

Some common types of benign bone tumors — and conditions that are commonly grouped with tumors — include:

• Nonossifying fibroma

• Unicameral (simple) bone cyst

• Osteochondroma

• Giant cell tumor

• Enchondroma

• Fibrous dysplasia

• Chondroblastoma

• Aneurysmal bone cyst

• Osteoid osteoma
   

Cause
 

For most bone tumors the cause is unknown.
 

Symptoms
 

Patients with a bone tumor will often experience pain in the area of the tumor. This pain is generally described as dull and aching.  It may worsen at night and increase with activity.
 

Other symptoms of a bone tumor can include fever and night sweats.
 

Many patients will not have any symptoms, but will note a painless mass instead.
 

Although bone tumors are not caused by trauma, an injury can sometimes cause a tumor to start hurting. Injury can also cause a bone that is weakened by a tumor to fracture, or break. This may be severely painful.
 

Occasionally, benign tumors may be discovered incidentally when an X-ray is taken for another reason, such as a sprained ankle or knee injury.

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Doctor Examination
 

Infections, stress fractures, and other non-tumor conditions can all closely resemble tumors. To be sure you have a bone tumor, your doctor will conduct a thorough evaluation and order a number of tests.
 

Medical History
 

As part of the examination, your doctor will take a complete medical history. They will ask about your general health, medications you take, and your current symptoms. Your doctor will also want to know if you or any family member has a history of any tumor or cancer.
 

Physical Examination
 

Your doctor will perform a thorough physical examination, focusing on the tumor mass. They will look for:

• Swelling or tenderness in the area of the tumor

• Changes in the overlying skin

• The presence of a mass

• Any effect the tumor might have on nearby joints
   

In some cases, your doctor will examine other parts of your body to rule out cancers that can spread to bone.
 

Tests
 

X-rays. X-rays provide images of dense structures, such as bone. In most cases, your doctor will order an X-ray to help diagnose a bone tumor. Different types of tumors may look different on X-ray. Some dissolve bone or make a hole in the bone. Others cause additional bone to form. Some may do both.

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Nonsurgical Treatment
 

Benign Tumors
If your tumor is benign, your doctor may recommend just monitoring it closely to see if it changes. During this time, you may need periodic follow-up X-rays or other tests.
 

Some benign tumors can be treated effectively with medication. Some will disappear over time without surgery. 
 

Malignant Tumors

If you have bone cancer, treatment will include a team of doctors from different medical specialties working together to provide care. Some will be oncologists — doctors who specialize in cancer treatment. Your team may include an orthopaedic oncologist, medical oncologist, radiation oncologist, radiologist, and pathologist. The goal of treatment is to cure the cancer while maintaining function, as best as possible, in the part of the body affected by the tumor.
 

Treatment depends upon several factors, including the stage of the cancer. If the cancer is localized, cancer cells are contained to the tumor and the immediate surrounding area. When the cancer has reached a metastatic stage, it has spread elsewhere in the body and may be more serious and harder to cure.
 

Doctors often combine several methods to treat malignant bone tumors:

• Radiation therapy. Radiation therapy uses high-dose X-rays to kill cancer cells and shrink tumors. This only treats the cancer in the area of the beam. It does not treat cancer elsewhere in the body. Your doctor will determine if radiation therapy is the best choice of treatment in your situation.

• Chemotherapy (systemic treatment). Chemotherapy is often used to kill tumor cells when they have spread into the bloodstream but cannot yet be detected on tests and scans. It is generally used when cancerous tumors have a very high chance of spreading. Chemotherapy is usually given intravenously (injection into a vein) or in a pill or capsule that is swallowed.
   

Generally, malignant tumors are removed by surgery. Often, radiation therapy and chemotherapy are used in combination with surgery.
 

Surgical Treatment
 

Benign Tumors

In some cases, your doctor may recommend removing the tumor (excision) or another surgical technique to reduce the risk of fracture and disability. Some tumors may come back, even repeatedly, after appropriate treatment. Rarely, certain benign tumors can spread or become cancerous (metastasize).
 

Malignant Tumors

Limb salvage surgery. This surgery removes the cancerous section of bone but keeps nearby muscles, tendons, nerves, and blood vessels intact where possible. The surgeon will take out the tumor and a portion of healthy tissue around it. The excised bone is replaced with a metallic implant (prosthesis), bone from elsewhere in your body, or bone from a donor.
 

Amputation. Amputation is surgery to remove all or part of an arm or leg. It is usually used when a tumor is large and/or nerves and blood vessels are involved. A prosthetic limb can aid function after amputation.
 

Recovery
 

The length and complexity of your recovery will depend upon the type of tumor as well as what type of procedure was performed.
 

When treatment is finished, your doctor may order more -Xrays and other imaging studies to confirm that the tumor is actually gone.
 

After treatment, you will continue to see your doctor for regular follow-up visits and tests every few months. Even though the tumor has disappeared, it is important to monitor your body for signs of recurrence. Tumors that come back may pose serious problems so it is important to detect them early.